Job Title:Senior Research Scientist Location:New York, NY,
Company:Merck Industry Sector:Agribusiness Salary:Competetive Job Description:Job Description
Attention NJ Applicants: In April 2020, our Company announced plans to consolidate our New Jersey campuses into a single New Jersey headquarters location in Rahway, NJ by 2023. Therefore, the NJ work location for this role will be temporarily based and the exact timing of the departmental move to Rahway, NJ will be communicated at a future date.
The Screening & Compound Profiling Group is seeking a highly motivated Senior Scientist with a strong background in screening and disease area biology, utilizing CRISPR gene knockout technology in our Quantitative Biosciences Department at our Research Laboratories in Kenilworth, NJ. Ideally you will have experience using CRISPR in a high- throughput arrayed format and your primary responsibilities will be to implement arrayed CRISPR at scale to support target and lead discovery across oncology, immunology, neuroscience, and cardiovascular disease areas. The ideal candidate will have experience with a variety of cell-based assays, with an emphasis on complex cellular models and high-content image analysis and functional genomics. Knowledge and understanding of miniaturized assays (384w/ 1536w) and downstream detectors ranging from standard luminescence-/fluorescence-based readouts to imaging and cell-microarray based platforms is desired. Using innovative thinking, state-of-the-art facilities, and robust scientific methodology we collaborate to discover the next medical breakthrough.
Work independently and as a Team member with Integrity | Precision | Accomplishment | Motivational Ambition | Respect | Inclusion
Experience using arrayed CRISPR gene knockout screening at scale in multi-well plates.
Experienced running CRISPR knockout screens in pooled or arrayed formats and experienced in validating and optimizing conditions for CRISPR gene editing.
Cellular assay development with proficiency in high-content screening and image analysis.
Focus on high throughput (HT)-complex cell models (3D, iPSC, co-culture systems).
Collaborate with Project teams across the company to develop innovative approaches to target-based and phenotypic screening for small molecule discovery efforts.
Solid understanding of data analysis workflows and statistical principles as well as AI/ML used in screening
Bachelor or Master or PhD degree
Bachelor's degree: with 10 years + experience | Master's Degree: with 4 years' + experience | PhD Degree: with zero years' experience(All three degree level experience must be in assay development and high throughput screening, with the ability to succeed in a collaborative, highly matrixed environment)
We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we "follow the science" that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.
Who we are ...
We are known as Merck & Co., Inc., Rahway, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.
What we look for ...
Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us-and start making your impact today.
NOTICE FOR INTERNAL APPLICANTS
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
Residents of Colorado
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For positions located in the United States and Puerto Rico - Subject to applicable law, all new hires (including internal transfers) must demonstrate that they are fully vaccinated against COVID-19 or that they qualify for a medical or religious exemption to this vaccination requirement. New hires (including internal transfers) to a position that, as determined by the Company, requires routine collaboration with external stakeholders (such as roles in health services or customer-facing commercial or research-based roles) ("Customer-Facing Role") who are not vaccinated must qualify for a medical or religious exemption and be in a position that the Company determines can accommodate unvaccinated employees without causing an undue burden to business operations. If, following dialog with the candidate as appropriate, it is determined that the candidate either a) does not qualify for a religious or medical exemption or, b) for candidates applying for Customer-Facing roles, it is determined that allowing the candidate to work without vaccination would cause an undue burden to the Company, the candidate will be ineligible for hire or transfer, or any offer of employment or transfer (if applicable) will be revoked. Please note that notwithstanding the approval of any reasonable accommodation, the Company reserves the right to monitor, modify, or revoke any such accommodation if it is determined, following dialog with the employee, that the accommodation is no longer effective or results in an undue burden to the Company.
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US and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
For more information about personal rights under Equal Employment Opportunity, visit:
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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.
Under New York City law, the Company is required to provide a reasonable estimate of the salary range for this job. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate's relevant skills, experience, and education.
Expected salary range: $96,700.00 - $164,500.00
Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status: Regular
VISA Sponsorship: Yes
Travel Requirements: 10%
Flexible Work Arrangements: Work Week
Valid Driving License:
Number of Openings: 1
To apply please click on APPLY TO THIS POSITION
Job Post Date: 11/03/22
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