Corteva Agriscience, the Agriculture Division of DowDuPont, is seeking a Research/Senior Research Toxicologist to support crop protection chemical metabolism and toxicokinetic studies within the Metabolism and Analytical group at Haskell Global Center for Health Sciences located in Newark, Delaware. The successful candidate will provide technical leadership and perform discovery and regulatory toxicokinetic and ADME studies in support of safety assessment of crop protection products. This group maintains a key role in consulting, research and safety testing as part of Corteva Agrisciences commitment to protecting human health and the environment.
- Design, conduct, interpret and report results for discovery (non-GLP) and regulatory (GLP) studies in toxicokinetics or ADME (absorption, distribution, metabolism and excretion) to advance the crop protection chemical discovery and registration pipelines;
- Provide technical leadership and guidance to junior scientific staff;
- Provide subject matter expertise for the ADME sciences within the Global Human Health Assessment function;
- Communicate findings to business and scientific audiences, through both oral presentations and written technical reports and manuscripts.
- Ph.D. in pharmacokinetics, chemical metabolism or related area with at least two years of relevant experience. Or, BS or MS degree in related discipline with minimum 15 years relevant experience.
- Demonstrated experience and expertise in in vitro and in vivo ADME studies;
- Thorough knowledge and expertise in mammalian metabolism and toxicokinetics/pharmacokinetics;
- Demonstrated ability to effectively function as a member of a high-performance team;
- Strong written and oral communication skills that allow dissemination of complex technical issues in a clear, concise manner to a variety of scientific and non-scientific audiences.
- Experience in working in a GLP (Good Laboratory Practice) environment;
- Experience working safely with radioactivity, including carbon-14;
- Experience in computational approaches for the prediction of mammalian metabolism and pharmacokinetics;
- Experience using commercial pharmacokinetic/toxicokinetic modeling software (e.g. Phoenix WinNonlin);
- Experience in non-compartmental, compartmental and PBPK modeling.
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Job Post Date: 01/19/19